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Dr. Chak Kwong CHENG, Andy

 

SCI-indexed publications
  • Pu Y, Cheng CK, Zhang H, Luo J, Wang L, Tomlinson T, Huang Y (2023) Molecular mechanisms and therapeutic perspectives of peroxisome proliferator-activated receptor α agonists in cardiovascular health and diseases. Medicinal Research Reviews 43(6):2086-2114.
  • Jiang M, Ding H, Huang Y, Cheng CK, Lau CW, Xia Y, Yao X, Wang L, Huang Y (2023) Thioridazine protects against disturbed flow-induced atherosclerosis by inhibiting RhoA/YAP-mediated endothelial inflammation. Acta Pharmacologica Sinica 44(10):1977-1988.
  • Cheng CK, Huang Y (2023) Oral microbiome: a doubtful predictor but potential target of cardiovascular diseases. Medical Review 3(3):209-213.
  • Cheng CK, Ding H, Jiang M, Yin H, Gollasch M, Huang Y (2023) Perivascular adipose tissue: Fine-tuner of vascular redox status and inflammation. Redox Biology 62:102683
  • Luo JY, Cheng CK, Gou L, He L, Zhao L, Zhang Y, Wang L, Lau CW, Chen AF, *Huang Y (2023) Induction of KLF2 by exercise activates eNOS to improve vasodilatation in diabetic mice. Diabetes 72(9):1330-1342 (Co-first author)
  • Cheng CK, Lin X, Pu Y, Tse KYJ, Wang Y, Zhang CL, Cao X, Lau CW, Huang J, He L, Luo JY, Shih YT, Wan S, Ng CF, Wang L, Ma CWR, JJ Chiu, Chan TF, Tian XY & Huang Y (2022) SOX4 is a novel phenotypic regulator of endothelial cells in atherosclerosis revealed by single-cell analysis. Journal of Advanced Research 43:187-203. 
  • Luo JY, Cheng CK, He L, Pu Y, Zhang Y, Lin X, Xu A, Lau CW, Tian XY, Ma RCW, Jo H & Huang Y (2022) Endothelial UCP2 is a mechanosensitive suppressor of atherosclerosis. Circulation Research 131(5):424-441. (Co-first author)
  • Cheng CK, Shang W, Liu J, Cheang WS, Wang Y, Xiang L, Lau CW, Luo JY, Ng CF, Huang Y, Wang L (2022) Activation of AMPK/miR-181b Axis Alleviates Endothelial Dysfunction and Vascular Inflammation in Diabetic Mice. Antioxidants 11(6):1137 (17 pages)
  • Wang L, Cheng CK, Yi M, Lui KO, Huang Y (2022) Targeting endothelial dysfunction and inflammation. Journal of Molecular and Cellular Cardiology 168:58-67.
  • Teoh YCJ, Tian XY, Wong YPC, Lau CW, Cheng CK, Tang WLV, Chan CKR, Huang Y & Ng CF (2022) Endothelial dysfunction after androgen deprivation therapy and the possible underlying mechanisms. Prostate 82(1):13-25.
  • Cheng CK & Huang Y (2021) The gut-cardiovascular connection: new era for cardiovascular therapy. Medical Review 1(1):23-46. Special Issue on Cardiovascular Research.
  • Huang J, Pu Y, Zhang H, Xie L, He L, Zhang C, Cheng CK, Huo Y, Wan S, Chen S, Huang Y, Lau CW, Wang L, Huang Y & Luo JY (2021) Endothelial KLF2 mediates the suppressive effect of laminar flow on vascular calcification by inhibiting BMP/SMAD1/5 signaling. Circulation Research 129(4):e87-e100.
  • Cheng CK, Luo JY, Lau CW, Cho WCS, Ng CF, Ma RCW, Tian XY & Huang Y (2021) A GLP-1 analog lowers ER stress and enhances protein folding to ameliorate homocysteine-induced endothelial dysfunction. Acta Pharmacological Sinica 42(10):1598-1609.
  • Cheng CK, Wang C, Shang W, Lau CW, Luo JY, Wang L & Huang Y (2021) A high methionine and low folate diet alters glucose homeostasis and gut microbiome. Biochemistry and Biophysics Reports 24 (March 2021): article 100921
  • Zhao S, Cheng CK, Zhang CL & Huang Y (2020) Interplay between oxidative stress, cyclooxygenases, and prostanoids in cardiovascular diseases. Antioxidants & Redox Signaling 34(10):784-799 with Cover Image. (Co-first author)
  • Cheng CK, Luo JY, Lau CW, Chen ZY, Tian XY & *Huang Y (2019) Pharmacological Basis and New Insights of Resveratrol Action in the Cardiovascular System. British Journal of Pharmacology 177(6):1258-1277.
  • Cheang WS, Wong WT, Wang L, Cheng CK, Lau CW, Ma RCW, Xu A, Wang N, Huang Y & Tian XY (2018) Resveratrol ameliorates endothelial dysfunction in diabetic and obese mice through sirtuin 1 and peroxisome proliferator-activated receptor δ.Pharmacological Research 139:384-394.
  • Zhang L, Tian XY, Chan C, Bai Q, Cheng CK, Chen F, Cheung M, Yin B, Yang H, Yung WY, Chen Z, Ding F, Leung K, Zhang C, Huang Y, Lau YW & Choi CH (2018) Promoting the delivery of nanoparticles to atherosclerotic plaques by DNA coating. ACS Applied Materials & Interfaces 11(15):13888-13904.
  • Cheng CK, Abu Bakar H, Gollasch M & Huang Y (2018) Perivascular adipose tissue: the sixth man of the cardiovascular system. Cardiovascular Drugs and Therapy 32(5):481-502.
  • Chan KW, Zhang L, Cheng CK, Yang H, Huang Y, Tian XY & Choi CH (2018) Recent advances in managing atherosclerosis via nanomedicine. Small 14(4):1702793 (16 pages)